We accelerate microbiome research
and develop new methods for manipulating microbiomes
to improve human health and benefit the environment.
UC San Diego is a world-leader in microbiome research, biomedical engineering, quantitative measurements and modeling, cellular and chemical imaging, drug discovery, "omics" sciences and much more. We draw interdisciplinary teams of these researchers together to push the boundaries of human understanding of microbiomes — the distinct constellations of bacteria, viruses and other microorganisms that live within and around humans, other species and the environment.
Scientists at the University of California San Diego have reported in the latest publication of Nature Biotechnology on a new type of tool to easily search for mass spectrometry (MS) data instead. This new web-enabled small-molecule MS search engine, called MASST - short for Mass Spectrometry Search Tool, is a starting point for enabling data-driven discovery of mass spectrometry data in the public domain and enables the reuse of public data and its related knowledge.
A paper in Cell Systems by leading co-authors Dr. Pavel Pevzner and his graduate student, Bahar Behsaz, alongside collaborators from around the world, presents the new CycloNovo algorithm that identifies cyclopeptide spectra in a haystack of all peptides (a vast majority of peptides are linear) and decodes them by analyzing large MS datasets.